Histamine intolerance – Q and A with Dr Janice Joneja. Dr Joneja, whose detailed article on histamine intolerance you can read here, will answer your questions. However, please be aware that Dr Joneja cannot diagnose or provide consultations for individuals. Please email Foods. Matter with your queries (including your gender and your approximate age) and we will pass them on to Dr Joneja. I know I have food allergies but how do I tell the difference between food allergies and histamine/tyramine intolerance?? Could histamine and excess copper could be implicated in severe and chronic hives?? N. B. You can buy all of Dr Joneja's books here in the UK or here in the US and you can buy DAO supplements here in the UK or here in the US. How to tell the difference between food allergy and histamine/tyramine intolerance. Question: I'm a 4. Food issues started at a very early age after my mother stopped breast feeding. I wouldn't drink cows milk and was a fussy eater. I had to give up red meat at 1. In my early 2. 0's I became vegetarian but still I had issues, always nauseous and anxious. In my mid 2. 0's I had a psychosis and have had several recurring episodes mainly centred around extreme anxiety and fear. I currently have a myriad of symptoms which include, nausea, anxiety, fear, headaches - behind right eye, build up of intense pressure in solar plexus and burping releases it. It's not normal burping it's painful before I burp and the burp releases the pressure, Itchy jaw line, tingling face, rash on neck and chest, aching joints - especially knees, waking at night feeling dizzy. I still feel sick after I eat and I have crippling headaches which last around 4. I feel much better and like I'm making progress towards understanding my triggers and the ways in which I can heal. My question is how do I tell the difference between food allergies and histamine intolerance as I feel I have both. And how would I treat both issues going forward as I already have a limited diet and I want to make sure I'm getting enough nutrition. Dr Joneja says: As you know, it is not possible for me to comment on specific cases in this forum, so I will answer your questions in a general discussion. It is certainly possible for a person to have both histamine intolerance and food allergies. You will find detailed information about all of this in Dr Joneja’s book, “Dealing with Food Allergies” which contains detailed information about this process. You can buy all of Dr Joneja's books here in the UK or here in the US. Food Intolerance. Study A&P CH23 Digestive System flashcards. Play games, take quizzes, print and more with Easy Notecards.
Intolerance to a food does not involve the immune system and antibodies are not produced against food molecules. Symptoms result from a reduced ability of the body to process components of the food, often due to a deficiency in the enzymes required for their metabolism, absorption, or utilisation. The reaction occurs when the level of the metabolite (the food component) exceeds the body’s ability to process it; this is called the person’s limit of tolerance, above which symptoms develop. You can buy all of Dr Joneja's books here in the UK or here in the US. The Mastocytosis Canada website provides my complete histamine and tyramine restricted diet on- line here. A registered dietitian will be able to help you with this and I urge you to enlist one’s assistance promptly. Urticaria, PUPPS and pregnancy – is there a connection? Question: My doctor and I are playing with the possibility that I have developed Histamine Intolerance. I am 4. 2 years old and have never had hives like this before, except once. When I was pregnant with my first child I had Puppps, which has very similar symptoms. About 2 months ago, I started getting welts (hives). It started out slowly and after about a month the hives covered nearly all of my body and were huge welts. They have always been terribly itchy. My first question is: Can a person develop this problem/disease later on in life? My chiropractor was under the impression that this was something that some children tend to have and either get better or it continues through their adult life. Histamine H2 receptors are found on gastric parietal cells, which produce hydrochloric acid (HCI) in the stomach. Though too little can cause inadequate digestion. HCl is one of the many chemicals released in our stomach when we eat a meal. About a month ago, I started taking steroids to try and get rid of the symptoms while we took tests to figure out what caused it. While on steroids, the hives went away, but when we started reducing the steroids they came back. I am no longer on steroids. I have started following your histamine restrictive diet. My 2nd question is: Since so many citrus fruits are NOT allowed on the diet, is citric acid that has been included in other foods allowed or is that ALSO restricted. My 3rd question is regarding all soy products that have been added into other foods, like soy lecithin and others. Are ALL soy products added into other things supposed to be avoided? Dr Joneja says: PUPPP is short for pruritic urticarial papules and plaques of pregnancy. Oestrogen and progesterone levels can profoundly affect the release and activity of histamine in some women Please see this article and this one for more information. Because histamine is the most important mediator in urticaria (hives), such a change in levels is often sufficient to trigger the onset of hives such as you have described. I would think that your chiropractor was referring to food allergy rather than histamine intolerance. See the bottom of this article for foods to avoid. Citric acid as an ingredient in manufactured foods is allowed. How long should I continue to keep taking Daosin for maximum efficacy? Are there any adverse side effects of the medicine that I should be aware of? Is there any prevention / precaution to be taken? Please see my histamine- restricted diet in Dealing with Food Allergies. You can buy all of Dr Joneja's books here in the UK or here in the US and you can buy DAO supplements here in the UK or here in the US. Freeze dried meat. Question: What are the histamine levels of freeze- dried meat? Dr Joneja says: A quick answer is: the same as before the meat was freeze- dried. Freeze- drying is a process involving fast freezing and dehydration. It will remain exactly the same as it was before the freeze- drying process. Facial rash, low energy, burning eyes, anxiety attacks, hair loss, weight loss and poor sleep. What led to my symptoms were a 6- month course of Naproxen 2. Flagyl yearly for Blastocystis hominis which has been living in my guts for at least 3 years. The Naproxen was for hypersensitivity in the vaginal/urinary area following repeated candida/bacterial vaginosis/urinary tract infections. My functional medicine doctor thinks that one of the causes can be histaminosis and has put me on a antihistamine diet and Daosin. Do you agree with his diagnosis? Dr Joneja says: As you are no doubt aware, dyspepsia with symptoms such as acid reflux, heart burn, and sore throat can have several different causes. Please read my articles on histamine intolerance and the histamine- restricted diet here. For more questions and Dr Joneja's answers see the top of the page. More on anxiety, panic attacks and histamine intolerance Question: I am female, aged 4. Here is a brief synopsis of my health history: Anxiety as young child with no major trauma — repeating behaviors/rituals, nightmares. Digestive issues during childhood— cramping with dairy. Repeated sinus infections, strep throat and yeast infections during 2. External vaginal itching beginning in teenage years – still continues and seems to be connected to foods consumed: corn, dairy, wheat seem to cause it. Early 3. 0s: diagnosed with systemic yeast infection. Identified multiple food sensitivities: dairy, gluten, corn — eating gluten causes puffy, red skin on my face; sinus congestion from dairy, corn, and gluten. Drinking alcohol also causes puffy, red skin on my face regardless of the alcohol type Continuing, reoccurring vaginal infections: beta strep, mersa, yeast — treated with multiple rounds of antibiotics. Early 4. 0s: diagnosed with SIBO — followed treatment plan, digestion improved — all vaginal infections ended for first time in 2. Age 3. 6 developed intense period cramps that continue to today — intense pain during menstruation. Increasing anxiety beginning at age 3. Age 4. 3 developed panic attacks and anxiety to a level that interferes with daily life — doesn’t seem directly related to circumstances — extreme dizziness with tingling and burning in head, heart racing. For the last 1. 0 years I have followed a good diet that is mostly gluten free and includes lots of vegetables. Furthermore, whenever itching is a symptom we can be fairly confident that excess histamine is involved. So it would seem that over the years you have been experiencing fairly high levels of histamine from a variety of sources. Your major concern at the moment is frequent panic attacks and anxiety. Also see my article here. If you find that are you free from these panic episodes while following the diet you can be reasonably certain that histamine excess is indeed contributing to the condition. Diet and supplements aren't enough to prevent the increase in symptoms and I am wondering if there are any tips, tricks or advice that addresses the hormonal fluctuations that occur at those times of the month. I would so happy if I could avoid those monthly flare ups. Answer: It is good to hear that you have been able to manage your symptoms by controlling your histamine level. As you are aware, hormonal fluctuations contribute quite significantly to histamine sensitivity, as oestrogen and progesterone influence histamine metabolism. Both hormone levels change at ovulation and just prior to the onset of menstruation and many women experience an increase in histamine, and therefore occurrence or worsening of symptoms, at those times. Often, a histamine- restricted diet is not adequate in keeping histamine levels below a person’s limit of tolerance (the level above which symptoms appear) when endogenous histamine (histamine produced within the body) rises significantly. At these times you might try controlling your symptoms of histamine excess with an antihistamine. Stomach and Duodenum . The first part of the small intestine is known as the duodenum. The stomach varies considerably in size, shape and position but lies in the upper central part of the abdomen behind the lower ribs. Although it is a single organ, several different parts of the stomach exist: the fundus, body, antrum and pylorus. Food passes through the pylorus and into the duodenum where further digestion occurs. An internal image of a healthy stomach. The stomach wall is composed of four layers. The inner lining (mucosa) consists of millions of microscopic glands which secrete gastric juices. Beneath this is a supporting layer (submucosa) and beneath this is the muscle layer. This is responsible for stomach contractions and emptying. Finally there is a thin outer covering known as the serosa. The stomach and duodenum have a rich blood supply, derived from the aorta (the main artery in the body) and are also supplied by nerves from the spinal cord. An iillustration of the stomach and its layers. Function and Control. The stomach carries out several different functions. It acts as the major store for food during a meal and can hold up to 1. Special cells (parietal cells) in the glands of the inner lining of the stomach secrete powerful hydrochloric acid that help break down food in the stomach. Other special cells release protein- digesting enzymes (pepsinogens) which become active in the acid environment and begin digesting protein. The stomach secretes a number of other important substances including hormones to regulate the functions of the stomach, mucus to protect the gastric lining from damage by acid, and a substance (intrinsic factor) which is necessary for the body to absorb vitamin B1. An internal image of a healthy duodenum. Coordinated contractions of the stomach are important for grinding and mixing ingested food with the gastric secretions. This ensures good mixing of stomach contents and also helps to filter out partially digested food to prevent large pieces from entering the duodenum. Lastly, partially digested food and liquids are carefully emptied from the stomach, through the pylorus, into the duodenum. These processes of secreting gastric juices, mixing food and gastric emptying are normally carefully regulated and involve the coordinated action of hormones, nerves, and muscles. Once food enters the duodenum, its acidity is neutralized by mixing with alkaline juices from the pancreas and bile in preparation for further digestion and absorption lower down the small intestine. Dysfunction. Disorders of the stomach and the duodenum are extremely common and a considerable source of suffering in the population. Upper abdominal pain, indigestion and heartburn may affect up to 2. Problems may arise from a number of different mechanisms and lead to a variety of symptoms. The integrity of the inner lining (mucosa) of the stomach depends on a careful balance between the . Disruption of this balance caused by too much acid (or weakened defense) can result in erosions or ulcers with symptoms including upper abdominal pain, indigestion or heartburn, nausea and/or vomiting. In other patients, symptoms may result from problems with stomach emptying. This can either be the result of a physical blockage (i. Symptoms include abdominal pain, bloating, nausea, vomiting after meals, lack of appetite and early satiety (inability to eat a full meal or feeling full after only a small amount of food). Erosions, ulcers and tumors may cause bleeding. If the bleeding is brisk and of sufficient quantity it may result in vomiting of bright red blood (hematemesis). Blood which has been in the stomach for any length of time undergoes partial digestion and turns black in color. This leads to vomiting of black fluid (. A small percentage of ulcers and other abnormalities in the stomach bleed very slowly over a long time and the patient is unaware of the bleeding. Eventually the body's iron stores run out and anemia develops. Gastrointestinal bleeding is discussed further below. Ulcers, tumors and other stomach problems may all produce very similar symptoms and it is not possible to determine the cause from symptoms alone. Patients with persistent or worrying symptoms require investigation, usually by endoscopy, to make a diagnosis and select appropriate treatment. Health Maintenance. Diet. Diet is believed to be important in the development of upper abdominal symptoms but there is little scientific evidence to incriminate individual foods or dietary components in causing particular symptoms. There is no specific diet which is known either to predispose to (or protect against) the development of peptic ulcers. In general, a sensible, balanced and healthy diet is recommended but people should avoid foods which they feel clearly upset their stomachs or provoke symptoms. Regular, unhurried meals are also important. Smoking. Smoking is an important factor in causing disorders of the stomach and duodenum. Tobacco contains compounds which increases acid production, impair production of protective mucus and damage the lining of the stomach, thereby predisposing to erosion and ulcers. Excess alcohol intake, especially spirits or hard liquor, irritates the gastric lining and may also play a role in causing gastritis, ulcers, and gastric cancer. A variety of medications may cause problems in the stomach and duodenum. Aspirin and other anti- inflammatory drugs (non- steroidal anti- inflammatory drugs, NSAID's) used to treat muscular and arthritic pain, commonly damage the stomach lining and cause erosions, ulcers and bleeding from the stomach and duodenum. Other medications interfere with gastric emptying and cause nausea, bloating or vomiting. If you suffer from problems with your stomach, you should always consult your doctor before taking any new medications. The role of psychological stress in the development of symptoms of indigestion and peptic ulcer disease is not clear. Periods of stress can make most medical conditions worse but whether stress specifically predisposes people to the development of peptic ulcers is not clear at present. Related Pages. Organs. Symptoms. Diseases.
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